The previous posts gave great advice too. CG did a great job of balancing settings with the slider settings when they implemented the new engine in Vray 3. I always recommend going back to default settings (for everything) and start from there. (I've had few tonight, so excuse any #%$^^*) hope you took my humor in stride.

005.what else are you planning on denoising? Denoiser set to 'strong'.holy crap, your noise level is already set to. (radius of 10? your whole render is gonna be AO.) but seriously, turn it off.it's probably doubling your render time while decreasing the quality by half.and it's another thing you could do in seconds in photoshop if you learn the proper technique. Come on.turn off 'ambient occlusion' already. Light Cache: your subdivs are incredibly low for a low light interior, while your sample rate is cranked up with a. Maybe do some region renders at more like 20-30 and compare quality vs time to the 50's. 90 subdivs is ok, could even go higher depending on how your quality is looking in test renders., but 50 interp rate? Not sure why that would be needed. irradiance map: 0 max rate.thats pretty high.once you reset to medium you'll be at -3/-1. Try taking the max down to 8 (or even 6) and see if that works for you Also after switching off 'progressive' you'll get some more settings here, also. Once you start off with default medium setting, try the default noise setting and go from there.lower as needed. 005 is a pretty low noise limit(as in a high setting). I see you have a bitmap in GI skylight override.do you a have a solid reason for this? I ask because a lot of times people use overrides when they actually don't need to override anything. It gives great results but at a premium, but you can do the same thing instantly in photoshop, instead of adding LOT of time to your render But bucket rendering is faster for production rendering (straight from Chaos Group) progressive mode is great for setting up lighting and testing scenes to get a quick preview, etc. Some other recommendations to easily cut down render time from glancing at your settings: Maybe go back to default 'medium' setting with the slider and start again from there. First of all, your setting aren't making too much sense.

Reset vray settings rhino 3.4